Sequence of human asialoglycoprotein receptor cDNA. An internal signal sequence for membrane insertion.

Deletion of the amino-terminal domain of asialoglycoprotein receptor H1 allows cleavage of the internal signal sequence.

Human asialoglycoprotein receptor H1 is a single-spanning membrane protein with an amino-terminal domain of 40 residues exposed to the cytoplasm and the carboxyl-terminal domain translocated to the exoplasmic side of the membrane. It has been shown earlier that the transmembrane segment functions as an internal uncleaved signal sequence for insertion into the endoplasmic reticulum. In a deletio...

Nucleotide sequence of a human cannabinoid receptor cDNA.

We described previously the cloning of putative G protein-coupled receptor by selective amplification using the polymerase chain reaction and degenerate primers corresponding to conserved regions of known receptors (1). This approach led to the cloning of the TSH receptor (2). Amongst the other characterized clones, HGMP08 appeared as preferentially expressed in the brain. The full coding regio...

cDNA sequence for human erythrocyte ankyrin.

The cDNA for human erythrocyte ankyrin has been isolated from a series of overlapping clones obtained from a reticulocyte cDNA library. The composite cDNA sequence has a large open reading frame of 5636 base pairs (bp) with the complete coding sequence for a polypeptide of 1879 amino acids with a predicted molecular mass of 206 kDa. The derived amino acid sequence contained 194 residues that we...

Nucleotide sequence of cDNA encoding for preprochymosin in native goat (Capra hircus) from Iran

Prochymosin is one of the most important aspartic proteinases used as a milk-clotting enzyme in cheese production. In the present investigation we report sequence of cDNA encoding goat ( Capra hircus ) preprochymosin and compare its nucleotide and deduced amino acid sequences with sequences of other ruminants preprochymosin. As bovine prochymosin, the caprine prochymosin cDNA encodes 365 amino ...

Porcine growth hormone receptor cDNA sequence.